Clinical Study of Rimonabant
The trials of Rimonabant have proved to be extremely successful.
Patients lost around 20 lbs after being treated with rimonabant
with an intake of 20 mg per day. After treatment with Acomplia
the metabolic syndrome 1 at baseline was reduced to half and reduction
in the plasma glucose has also been noted. It is expected by the
second half of 2006.
The study will prove whether Acomplia blocks the CB1 receptors
in the brain, if its affects alcohol consumption. A study conducted
on the animals proved that the CB1 receptors were blocked as the
animals consumed less alcohol. It reduces the urge to smoke and
reduces hunger pangs to a great extent.
A study proves that the pill has been successful in maintaining
weight loss at least two years. Those patients who were being treated
for anti - smoking, gained much less weight as compared to the other
drugs that were available. The intake of Acomplia/Zimulti has doubled
the chances of the individual quitting smoking to a great extent.
Acomplia/Zimulti was developed according to the hunger pangs cannabis
smokers underwent. It was noted that if cannabinoids could increase
the appetite, blocking the same could reduce the appetite. Screening
of the candidates include questions related to alcohol and drug
usage, physical examination, blood and urine tests and breath alcohol
test. A questionnaire had to be filled by the participants stating
the use of cigarettes, intake of alcohol, and their mental health
history.
A lock called the heparin lock is placed in a vein the participants
arm; it is needle that remains in the arm till the test is conducted.
During the test which lasts 30 minutes participants fill up a questionnaire
regarding their urge to drink and their mood.
The participants are given alcohol to consume within 5 minutes
and monitored for the next 50 minutes. The study thereafter ends
at 7pm and they are required to stay overnight in the hospital.
21 years to 45 years of age is the basic criteria for the study
and the weight of the males should be between 60 kg and 90 kg and
the weight of the females should be 45 kg to 80 kg.
It has been shown that 33% of the people using Acomplia lost 10%
of their body weight and have managed to keep their weight steady
for two years. The only side effects that were transient were: dizziness
and mild gastrointestinal effects.
Patients with significant presence of cardiovascular, infectious
diseases, or psychiatric disorders, pulmonary, metabolic, and individuals
with suicidal attempt have to be excluded. Patients, who have donated
blood within three months of their administration, also have to
be excluded from the same.
Conclusion:
After the studies conducted, it has been noted that Acomplia/Zimulti
is the most awaited drug, for its effectiveness against smoking
and obesity which has been quite successful. It has also helped
the type - II diabetes,that has been affecting the people all over
the world.
gyms
Acomplia
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